The bake time for salmon at 350 degrees Fahrenheit is 22 minutes if it’s cooked uncovered; you can shave a few minutes off by wrapping it in foil. However, for the best results, it’s better to cook baked salmon at 375 degrees. Wrap your fish in a foil pouch so it can steam in its own juices, then bake it at 375 for 15 to 20 minutes or until it flakes easily with a fork. If you like your salmon a bit crispy, uncover it at the end and pop it under the broiler for a minute or two.
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